Welcome Letter

Dear colleagues,

It is our pleasure to invite you to participate in The 8th International Conference on Prehypertension, Metabolic Disorders & Cardiovascular Disease, which will take place in Zagreb, Croatia, November 3-6, 2022.

Prehypertension is a part of the continuum from normotension to hypertension, among other causes, it is a part of a dynamic process of stiffening and aging of the arteries and of the heart with its consequences. Patients in the prehypertensive range will become finally hypertensive. Diseased arteries will not only participate in propagation of end organ damage but will enhance the progression of additional damage in the arteries, the heart, the kidney and the brain as well as in other organs in the patients body. Understanding the risk of borderline conditions in the metabolic syndrome will enable us to understand the nature of end organ damage and will create a possibility of better prevention, diagnosis and treatment of this continuous process.

Hypertension, Diabetes, Dyslipidemia and Obesity are considered as major risk factors for Atherosclerosis of cerebral, coronary, renal and peripheral arteries. This process causes development of Ischemic heart disease, obstruction to cerebral flow, renal failure and PVD. Clustering of these risk factors is very common and their accumulation causes faster propagation of end organ damage.

The diagnosis of risk factors, especially when they are clustered, justify multidisciplinary, aggressive therapeutic approach, which should be started as soon as possible with the earliest diagnosis.
The association of multiple CV risk factors enhances rate of progression of end organ damage and affects morbidity and mortality. The presence of multiple risk factors changes the prognosis of the patients and should affect our therapeutic approach- an area with insufficient information and guidelines.
Systolic blood pressure (BP) of less than 140 mm Hg and diastolic BP of less than 90 mm Hg were for years considered as normal. Mounting evidence suggest that BP in the high reference range is associated with an increased risk of cardiovascular disease.
In most developing countries and in the urban areas of many countries, one in five to one in three adults fall in the category of prehypertension. Recently published guidelines suggested change in the threshold levels to much lower levels than previously considered normal. This change caused scientific discussion and debate. Discussing recommendation and guidelines in the field have substantial public health importance and also enormous economic consequences.

The Conference will deal with all aspects related to early diagnosis, including innovative technologies and treatments as well as discussion of target organ damage, cardiac, renal, neurological and peripheral arteries. The conference will bring together professionals from the fields of Hypertension, Cardiology, Nephrology, Neurology, Endocrinology, Internal Medicine, Family Medicine and many more.

We hope that you will join us for what promises to be a stimulating professional and educational event and look forward to welcoming you in Zagreb.

Yours sincerely,

Chairmen
Reuven Zimlichman and Bojan Jelakovic

Honorary Chairmen
Stevo Julius and Giuseppe Mancia